HEXIDERM 100 ml
Hexiderm is used in cattle, horses, dogs, and cats as the treatment and preventive care both in the monotherapy and as part of the complex therapy of
- skin injuries (including bruises, abrasions, cut, bitten and puncture wounds);
- skin infections (including pyoderma, eczema, ulcers);
- simple and allergic dermatitis (including those complicated by secondary infection);
- treatment of burn wounds and surfaces (including between fingers, skin folds);
- gingivitis, stomatitis, periodontitis, alveolitis;
-postoperative oral cavity care;
- otitis media of various etiology (for cleaning the ear canal);
-postoperative care of the behind-the-ear and ear canal;
- balanitis, balanopostitis;
- vulvitis vaginitis;
-antiseptic treatment of skin and mucous membranes before catheterization and diagnostic procedures.
Hexiderm contains in 1 g as active ingredients: 20% chlorhexidine bigluconate 10 mg, benzocaine 10 mg, and excipients.
The drug is manufactured in a form of a homogeneous, colorless to white-gray opalescent gel-like mass. Yellowish color is allowed.
Gel for external use.
Antiseptic and disinfectants in combinations.
Hexiderm is packaged by 100 g in polymeric vials or bottles of appropriate capacity, sealed with screw caps (dispenser cap is allowed).
The combination Hexiderm drug with pronounced antimicrobial, antiinflammatory, and analgesic effects on the animal’s skin and mucous membranes. Chlorhexidine bigluconate is a dichlorine-containing derivative of biguanide. Provides antiseptic (antimicrobial, fungicidal, and viricidal) effect.
Chlorhexidine interacts with phosphate groups on the surface of the microbial cell, and the lipophilic groups contribute to the disaggregation of the lipoprotein membrane of bacteria, thereby violating the osmotic balance of bacterial cells, potassium and phosphorus release from them, which results in the bacterial death. The efficacy of chlorhexidine in the presence of blood and pus, various secretions, and organic substances has been clinically proven.
Benzocaine is a topical anesthetic for superficial anesthesia. It prevents the painful sensations in the endings of the sensitive nerves and conduct of pain impulses along the nerve fibers. It reduces the permeability of the cell membrane to Na+ ions, eliminates Ca2+ from receptors located on the inner surface of the membrane, blocks the formation and conduction of nerve impulses.
With external and topical application of the drug in therapeutic doses, the absorption of active substances into the blood does not occur.
According to the degree of exposure to the organism, Hexederm refers to low-risk substances.
For injuries, skin infections, dermatitis, burns, eczema, as well as for the treatment of sutures and disinfection of the skin before surgeries or catheterization: apply Hexiderm on the previously cleaned and dried skin or mucous membranes at the sites of injury, covering up to 1 cm of the surrounding area. Apply the drug as a thin layer, gently rubbing it from the periphery to the center. Before application, cut or shave the coat on the treated area, if necessary. Prevent licking of the drug by an animal within 15–20 minutes after its application. Treat an animal twice a day for 10–14 days. The treatment duration is determined on a case-by-case basis and depends on the nosological form and severity of disease.
Dental diseases: apply the drug as a thin layer to the inflamed areas of the mucous membrane of the animal’s oral cavity. Treat an animal twice a day for 10–14 days.
Otitis media of various etiology: firstly, clean the auricles and auditory canals thoroughly from earwax, crusts, and scabs with a swab moistened with a drug, and then place a small amount of gel into each ear. Treat an animal twice a day for 7–10 days. As the preventive care, use the drug once.
Balanitis, balanoposthitis, vulvitis, and vaginitis: apply Hexiderm after preliminary hygienic and antiseptic treatment of the skin and mucous membranes.
For balanitis and balanopostitis, apply the drug externally as a thin layer to the affected area twice a day for 7–10 days.
For vulvitis and vaginitis, apply Hexiderm externally and/or intravaginally. Apply a small amount of the drug on the affected skin of the vulva and/or vagina mucous membranes 1 to 2 times a day for 10 –14 days. For larger animals the drug may be administered with the use of gauze swabs. Applied the drug to a tampon and insert it into the vagina for 15 – 30 minutes. Do not use the drug when animals are sexually aroused.
If necessary, after 20 days, the course of application of the drug Hexiderm is repeated.
For any diseases, if there is no clinical improvement after 4-5 days after the start of treatment with Hexiderm, it is necessary to clarify the diagnosis and / or change the treatment regimen, or cancel the drug.
The specifics of the drug's effect during its first use and cancellation have not been established.
Violations of the dosage regimen and the drug administration regimen should be avoided, as this may lead to a decrease in its effectiveness. In case of missing the next use of the drug, it should be carried out as soon as possible in the same dose and according to the same scheme.
Interaction with other drugs
There is no information about the incompatibility of the Hexiderm drug with other drugs of pathogenetic and symptomatic therapy.
Side effects and complications
Side effects and complications in livestock when using the drug in accordance with this instruction, as a rule, are not observed. Individual local side effects may occur: itching, burning, irritation and dryness of the skin, allergic reactions, as well as staining of the enamel of teeth. In this case, the treatment with the drug should be discontinued and, if necessary, symptomatic therapy should be performed on the animal.
Application to pregnant and lactating female animals during pregnancy and feeding of the offspring, the drug is used under the supervision of a veterinarian based on an assessment of the ratio of the expected benefit to the possible risk of its use.
Contraindications
Contraindications to the use of the drug Hexiderm are increased individual sensitivity of poultry or livestock to its components (including in the anamnesis). It is forbidden to use the drug to livestock with damage to the eardrum. It is not allowed to use the drug in livestock younger than 2 months of age.
Overdose
Symptoms of overdose with the drug Hexiderm in livestock have not been established. In case of accidental ingestion of the drug and the appearance of signs of intoxication, general measures aimed at removing the drug from the organism are used, enterosorbents and symptomatic therapy are prescribed.
Interaction with other drugs
There is no information about the incompatibility of the Hexiderm drug with other drugs of pathogenetic and symptomatic therapy.
Specific instructions
Products of animal origin obtained after the application of the drug can be used without restrictions.
Measures of personal prevention
When using a product, the general rules of personal hygiene and safety provided for when using drugs should be observed. People with hypersensitivity to the components of the drug should avoid direct contact with it. In case of accidental contact of the drug with the skin or mucous membranes of the eyes, they must be rinsed with plenty of water. In case of allergic reactions or accidental ingestion of the components of the drug into the human body, you should immediately contact a medical institution (take the patient information leaflet or label with you).
Empty packaging from under the drug is prohibited to be used for household purposes, it is subject to disposal with household waste. The unused drug is disposed of in accordance with the requirements of the legislation.
Store the drug in the original closed package, protected from direct sunlight, separately from food and feed, at a temperature of 0 to +25°C.
Keep out of reach of children!
It is released without a prescription from a veterinarian.
The shelf life under storage conditions in the original closed package is 36 months.
Do not use after the expiration date.