Fenpraz forte suspension for large breed dogs

Fenpraz forte contains in 1 ml per 4 kg as active ingredients: fenbendazole 6 mg, pyrantel pamoate 56 mg, praziquantel 20 mg, ivermectin 0.024 mg, and excipients.

The drug is made in a form of light yellow suspension. Stratification of the suspension is allowed, which disappears after stirring.

Dosage form:

Suspension for oral administration.

Pharmacotherapeutic group:

Combined anthelmintic agent.

Fenpraz forte suspension, due to its combined composition, has a wide spectrum of anthelmintic action against round and ribbon helminths, as well as protozoa of the genus giardia, parasitic in dogs and cats, including Toxocara canis, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma caninum, Trichuris vulpis, Echinococcus granulosus, Echinococcus multilocularis, Taenia spp. Multiceps multiceps, Mesocestoides lineatus, Dipylidium caninum, Giardia spp., as well as larval phases of development (microfilariae) Dirofilaria immitis and Dirofilaria repens.

The mechanism of action of pyrantel pamoat consists in blocking neuromuscular transmission and violation of the permeability of cell membranes, inhibition of cholinesterase, which entails paralysis and death of the parasite.

The mechanism of action of praziquantel is based on the violation of glucose transport and microtubular function in helminths, inhibition of fumarate reductase activity and ATP synthesis, increased permeability of cell membranes and violation of muscle innervation, which leads to paralysis of the death of the parasite. Pyrantel pamoate and fenbendazole are partially absorbed into the intestine and excreted from the organism mainly with feces within 24-48 hours.

The mechanism of action of ivermectin, which is part of the drug, consists in its effect on the amount of chlorine ion current through the membranes of nerve and muscle cells of the parasite. The main target is glutamate-sensitive chlorine channels, as well as gamma-aminobutyric acid receptors. A change in the current of chlorine ions disrupts the conduction of nerve impulses, which leads to paralysis and death of the parasite. The maximum concentration of ivermectin in blood plasma is noted 9 hours after oral administration. Ivermectin is excreted from the body mainly with bile, feces and partially with urine.

According to the degree of exposure to the organism, Fenpraz forte refers to low-risk substances, in recommended doses, it is well tolerated by dogs.

Fenpraz forte suspension is given to the animal inside, once, individually, in the morning, at a dose of 1 ml per 4 kg of weight with a small amount of feed or forcibly poured into the cheek area using a syringe dispenser.

Before use, the bottle with the suspension must be thoroughly shaken. For therapeutic purposes, animals are dewormed according to indications, for preventive purposes – quarterly at the above dose. When deworming animals weighing less than 0.5 kg, immediately before use, 0.5 ml of boiled water is added to the measured dose of the suspension, thoroughly shaken and injected into the animal.

For the treatment of giardiasis, the drug is used in the same dosage, once a day, for 3 days. To reduce the number of circulating microfilariae in animals infected with Dirofaria immitis or Dirofilaria repens, the drug is prescribed once, once a month.

In order to prevent dirofilariasis, the suspension is used in the spring-summer-autumn period: once before the beginning of the summer of mosquitoes (March-April), then monthly from April to October, and for the last time in the season – 1 month after the end of the summer of mosquitoes (October-November).

It is also recommended to use the drug 10-14 days before vaccination or mating, 10 days before the expected delivery.

The peculiarities of the drug's action during its first use or cancellation were not revealed. Violations of the recommended timing of deworming of animals should be avoided In case of non-compliance with the established deadline for repeated treatments, the use of the drug should be resumed in the same dosage according to the same scheme. Before using the drug, a preliminary fasting diet and the use of laxatives before deworming is not required. When deworming animals, it is recommended to disinfect and disinfect their places of detention in order to avoid re-infection.

Side effects and complications when using the drug Fenpraz forte suspensions in accordance with this instruction, as a rule, are not observed.

With increased individual sensitivity of the animal to the components of the drug, the following clinical manifestations are possible: increased salivation, diarrhea or vomiting. These symptoms are short-lived, disappear spontaneously and do not require the use of other medications.

The drug is contraindicated in case of increased individual sensitivity of the animal to the components of the drug (including in the anamnesis). It is not recommended to deworm nursing and pregnant animals. It is not recommended to use the drug for kittens younger than 3 weeks of age.

With an overdose of the drug, depression, refusal of food, excessive salivation, diarrhea and vomiting may occur. In this case, symptomatic therapy is performed.

Fenpraz forte suspension is not recommended to be used simultaneously with piperazine and other drugs that inhibit cholinesterase, due to possible antagonistic effects.

The drug is not intended for use by food-producing animals.

When using a product, the general rules of personal hygiene and safety provided for when using drugs should be observed. Smoking, drinking and eating are prohibited during the usage. Empty packaging from under the drug is prohibited to be used for household purposes, it is subject to disposal with household waste.

In case of accidental contact of the drug with the skin or mucous membranes of the eyes, they must be rinsed with plenty of water.

People with hypersensitivity to the components of the drug should avoid direct contact with it. In case of accidental contact of the drug with the skin or mucous membranes of the eyes, they must be rinsed with plenty of water. In case of allergic reactions or accidental ingestion of the components of the drug into the human body, you should immediately contact a medical institution (take the instructions for use or label with you).

The drug is produced packaged in 20 ml in polymer vials, hermetically sealed with screw-on lids with the control of the first opening, packed in cardboard packs. Each consumer package is provided with instructions for use, a syringe dispenser and stickers for a veterinary passport.

Store the drug in the original closed package, protected from direct sunlight, separately from food and feed, at a temperature of 0 to +25°C.

Keep out of reach of children!

It is released without a prescription from a veterinarian.

The shelf life under storage conditions in the original closed package is 24 months from the manufacturing date. The drug is to be used within 3 weeks after the first opening of the primary package. 

After opening store in a dry and dark place at a temperature of 6-8 ° C no more than 3 weeks.

Do not use after the expiration date.